Dnaaf9 | dynein axonemal assembly factor 9

GeneMGI:1923029Synonyms: 4930402H24Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Nervous system Hematopoietic system

14 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition5 supporting datasetsDnaaf9tm1b(EUCOMM)HmguhomozygoteEarly adult2.45x10-12 
increased neutrophil cell number1 supporting datasetDnaaf9tm1b(EUCOMM)HmguhomozygoteEarly adult3.64x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Dnaaf9 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Dnaaf9tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dnaaf9tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Dnaaf9tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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