Pank1 | pantothenate kinase 1
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Liver/biliary system Behavior/neurological
18 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal liver morphology | 1 supporting dataset | Pank1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased locomotor activity | 2 supporting datasets | Pank1em1(IMPC)Mbp | homozygote | Early adult | 3.68x10-5 | ||
| small liver | 1 supporting dataset | Pank1em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Pank1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pank1.
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| Pank1em1(IMPC)Mbp | Exon Deletion | | mouse |