Anapc15 | anaphase promoting complex C subunit 15
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Embryo Growth/size/body region Nervous system Vision/eye Craniofacial Mortality/aging
13 No significant impact
3 Not tested
Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| embryonic growth retardation | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal placenta size | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal hindbrain morphology | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| edema | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
| abnormal midbrain morphology | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Anapc15tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * |
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| adrenal gland | heterozygote | Section images | 100% (1/1) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 50% (1/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | n/a | 87.5% (21/24) |
| esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
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