Anapc15 | anaphase promoting complex C subunit 15

GeneMGI:1922680Synonyms: 6330414C15Rik, 3200002M19Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Nervous system Vision/eye Craniofacial Mortality/aging

13 No significant impact

3 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

embryonic growth retardation1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal placenta size1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal neural tube closure1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal hindbrain morphology1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
abnormal placenta morphology1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
edema1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE15.5N/A * 
abnormal midbrain morphology1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
anophthalmia1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE15.5N/A * 
abnormal embryo size1 supporting datasetAnapc15tm1.1(KOMP)VlcghomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Anapc15tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Anapc15tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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