Rnase10 | ribonuclease, RNase A family, 10 (non-active)
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological
14 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased lean body mass | 2 supporting datasets | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 1.38x10-6 | ||
| decreased CD4-positive, alpha-beta T cell number | 1 supporting dataset | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.19x10-5 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 9.65x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 6.54x10-5 | ||
| decreased CD8-positive, alpha-beta T cell number | 1 supporting dataset | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 3.07x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Rnase10tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.32x10-5 |
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Human diseases caused by Rnase10 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rnase10.
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