Rnase10 | ribonuclease, RNase A family, 10 (non-active)

GeneMGI:1922269Synonyms: 4930474F22Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased lean body mass2 supporting datasetsRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult1.38x10-6 
decreased CD4-positive, alpha-beta T cell number1 supporting datasetRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult2.19x10-5 
decreased circulating triglyceride level1 supporting datasetRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult9.65x10-5 
decreased locomotor activity1 supporting datasetRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult6.54x10-5 
decreased CD8-positive, alpha-beta T cell number1 supporting datasetRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult3.07x10-5 
increased total body fat amount1 supporting datasetRnase10tm1a(EUCOMM)HmguhomozygoteEarly adult2.32x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnase10tm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
mouse
Rnase10tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Rnase10tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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