Syce1l | synaptonemal complex central element protein 1 like
Physiological systems
18 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
17 No significant impact
6 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| increased circulating free fatty acids level | 1 supporting dataset | Syce1ltm1.1(KOMP)Vlcg | homozygote | Early adult | 3.4x10-6 | ||
| increased circulating sodium level | 1 supporting dataset | Syce1ltm1.1(KOMP)Vlcg | homozygote | Early adult | 1.36x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
| colon | heterozygote | Section images | 100% (2/2) | 52.38% (22/42) |
| epididymis | heterozygote | Section images | 0% (0/1) | 87.5% (21/24) |
Human diseases caused by Syce1l mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Syce1l.
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| Syce1ltm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Syce1ltm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Syce1ltm92964(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |