Hhatl | hedgehog acyltransferase-like

GeneMGI:1922020Synonyms: 1110011D13Rik, Mitsugumin 56, +2 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Behavior/neurological Skeleton Mortality/aging

17 No significant impact

2 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity6 supporting datasetsHhatlem1(IMPC)MbphomozygoteEarly adult1.97x10-9 
no spontaneous movement1 supporting datasetHhatlem1(IMPC)MbphomozygoteE18.5N/A * 
increased freezing behavior1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult3.33x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult1.38x10-5 
decreased lean body mass1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult3.52x10-6 
no spontaneous movement1 supporting datasetHhatlem1(IMPC)MbpheterozygoteE18.5N/A * 
increased bone mineral content1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult3.45x10-8 
increased total body fat amount1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult1.96x10-8 
abnormal gait1 supporting datasetHhatlem1(IMPC)MbphomozygoteEarly adult4.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hhatlem1(IMPC)MbpExon Deletionmouse

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