Ralgps1 | Ral GEF with PH domain and SH3 binding motif 1

GeneMGI:1922008Synonyms: RALGPS1A, RALGEF2, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vocalization	1 supporting dataset	Ralgps1^em1(IMPC)J	homozygote	Early adult	2.42x10^-10
thrombocytopenia	1 supporting dataset	Ralgps1^em1(IMPC)J	homozygote	Early adult	2.34x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Ralgps1^em1(IMPC)J	homozygote	Early adult	8.21x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ralgps1.

Associated images

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Histopathology

There is no histopathology data found for Ralgps1.

IMPC related publications

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External links

No external links available for Ralgps1.

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*Ralgps1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Ralgps1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ralgps1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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