Pomk | protein-O-mannose kinase

GeneMGI:1921903Synonyms: 4930444A02Rik, Sgk196

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral density1 supporting datasetPomkem1(IMPC)HmguheterozygoteEarly adult1.96x10-6 
decreased startle reflex1 supporting datasetPomkem1(IMPC)HmguheterozygoteEarly adult3.48x10-5 
increased spleen weight1 supporting datasetPomkem1(IMPC)HmguheterozygoteEarly adult2.41x10-5 
abnormal kidney morphology1 supporting datasetPomkem1(IMPC)HmguheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetPomkem1(IMPC)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pomkem1(IMPC)HmguInter-exon deletionmouse
Pomktm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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