Cdkal1 | CDK5 regulatory subunit associated protein 1-like 1
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Behavior/neurological
17 No significant impact
5 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased exploration in new environment | 1 supporting dataset | Cdkal1tm2b(EUCOMM)Wtsi | homozygote | Early adult | 1.98x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Cdkal1tm2b(EUCOMM)Wtsi | homozygote | Early adult | 8.6x10-6 |
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Human diseases caused by Cdkal1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cdkal1.
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| Cdkal1tm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Cdkal1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cdkal1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Cdkal1tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cdkal1tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cdkal1tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |