Tspan17 | tetraspanin 17
Physiological systems
19 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
18 No significant impact
5 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating cholesterol level | 1 supporting dataset | Tspan17em1(IMPC)H | homozygote | Early adult | 1.59x10-5 | ||
| increased circulating iron level | 1 supporting dataset | Tspan17em1(IMPC)H | homozygote | Late adult | 1.4x10-7 |
| | | | | | | | | | |
Human diseases caused by Tspan17 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tspan17.
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| Tspan17em1(IMPC)H | Indel | | mouse |
| Tspan17em2(IMPC)H | Indel | | mouse |
| Tspan17tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Tspan17tm96618(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Tspan17tm96618(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |