Iqce | IQ motif containing E

GeneMGI:1921489Synonyms: 1700028P05Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness2 supporting datasetsIqcetm1b(EUCOMM)HmguhomozygoteEarly adult3.57x10-6 
increased circulating phosphate level1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult5.44x10-5 
increased mean corpuscular volume1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult2.39x10-7 
abnormal locomotor behavior1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult8x10-7 
increased neutrophil cell number1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult2.73x10-8 
decreased circulating glucose level1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult4.31x10-5 
decreased lymphocyte cell number1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult4.3x10-9 
tremors1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult4.82x10-6 
decreased circulating serum albumin level1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult2.88x10-5 
short tibia1 supporting datasetIqcetm1b(EUCOMM)HmguhomozygoteEarly adult6.59x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Iqcetm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Iqcetm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Iqcetm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Iqcetm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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