Rbm20 | RNA binding motif protein 20
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Nervous system Vision/eye Hematopoietic system Cardiovascular system
14 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating triglyceride level | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | 2.25x10-5 | ||
| absent optic nerve | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small spleen | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | 1.36x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | 2.94x10-5 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | 1.63x10-5 | ||
| abnormal heart shape | 1 supporting dataset | Rbm20em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Rbm20 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Rbm20.
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| Rbm20em1(IMPC)Mbp | Exon Deletion | | mouse |
| Rbm20tm82933(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |