Mark4 | MAP/microtubule affinity regulating kinase 4

GeneMGI:1920955Synonyms: Markl1, 2410090P21Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal skin morphology	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Early adult	1.12x10^-6
microphthalmia	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small testis	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Mark4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mark4.

Associated images

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Histopathology

There is no histopathology data found for Mark4.

IMPC related publications

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External links

No external links available for Mark4.

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*Mark4^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Mark4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Mark4^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mark4^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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