Rwdd3 | RWD domain containing 3
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging Cardiovascular system
15 No significant impact
6 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased grip strength | 3 supporting datasets | Rwdd3tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.65x10-7 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Rwdd3tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| prolonged ST segment | 1 supporting dataset | Rwdd3tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.01x10-5 |
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Human diseases caused by Rwdd3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rwdd3.
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| Rwdd3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Rwdd3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Rwdd3tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Rwdd3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |