Rwdd3 | RWD domain containing 3

GeneMGI:1920420Synonyms: RSUME, 3110037C01Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength3 supporting datasetsRwdd3tm1b(KOMP)WtsiheterozygoteEarly adult4.65x10-7 
preweaning lethality, complete penetrance1 supporting datasetRwdd3tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
prolonged ST segment1 supporting datasetRwdd3tm1b(KOMP)WtsiheterozygoteEarly adult4.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rwdd3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Rwdd3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Rwdd3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rwdd3tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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