Ccnt2 | cyclin T2

GeneMGI:1920199Synonyms: CycT2, 2900041I18Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Integument Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased total retina thickness	2 supporting datasets	Ccnt2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.32x10^-6
unresponsive to tactile stimuli	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Ccnt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal skin coloration	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.54x10^-5
male infertility	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal retina outer nuclear layer morphology	2 supporting datasets	Ccnt2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.85x10^-5
unresponsive to tactile stimuli	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	heterozygote	E18.5	N/A ^*
female infertility	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Ccnt2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.91x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccnt2.

Associated images

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Histopathology

There is no histopathology data found for Ccnt2.

IMPC related publications

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External links

No external links available for Ccnt2.

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*Ccnt2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ccnt2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ccnt2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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