Bbof1 | basal body orientation factor 1

GeneMGI:1920123Synonyms: 2900006K08Rik, Ccdc176

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating iron level1 supporting datasetBbof1em1(IMPC)MarchomozygoteEarly adult7.05x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetBbof1em1(IMPC)MarchomozygoteEarly adult1.24x10-8 
female infertility1 supporting datasetBbof1em1(IMPC)MarchomozygoteEarly adultN/A * 
increased basophil cell number1 supporting datasetBbof1em1(IMPC)MarchomozygoteEarly adult1.76x10-5 
male infertility1 supporting datasetBbof1em1(IMPC)MarchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Bbof1em1(IMPC)MarcDeletionmouse
Bbof1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bbof1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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