Csnk1g2 | casein kinase 1, gamma 2
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Muscle Hearing/vestibular/ear Vision/eye Respiratory system Hematopoietic system Cardiovascular system
12 No significant impact
5 Not tested
Data collections
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased cardiac muscle contractility | 2 supporting datasets | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.62x10-5 | ||
persistence of hyaloid vascular system | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.9x10-7 | ||
increased circulating phosphate level | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.83x10-5 | ||
increased circulating potassium level | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.52x10-6 | ||
increased pulmonary respiratory rate | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.46x10-5 | ||
increased mean corpuscular volume | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.71x10-15 | ||
abnormal retina blood vessel morphology | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.77x10-5 | ||
increased heart rate variability | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.52x10-7 | ||
decreased total retina thickness | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.24x10-5 | ||
abnormal auditory brainstem response | 1 supporting dataset | Csnk1g2tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.26x10-5 |
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External links
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Csnk1g2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Csnk1g2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |