Csnk1g2 | casein kinase 1, gamma 2

GeneMGI:1920014Synonyms: 2810429I12Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Muscle Hearing/vestibular/ear Vision/eye Respiratory system Hematopoietic system Cardiovascular system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased cardiac muscle contractility2 supporting datasetsCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult2.62x10-5 
persistence of hyaloid vascular system1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult5.9x10-7 
increased circulating phosphate level1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult2.83x10-5 
increased circulating potassium level1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult4.52x10-6 
increased pulmonary respiratory rate1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult9.46x10-5 
increased mean corpuscular volume1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult7.71x10-15 
abnormal retina blood vessel morphology1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult2.77x10-5 
increased heart rate variability1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult4.52x10-7 
decreased total retina thickness1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult1.24x10-5 
abnormal auditory brainstem response1 supporting datasetCsnk1g2tm1b(EUCOMM)WtsihomozygoteEarly adult5.26x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Csnk1g2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Csnk1g2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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