Naa50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit

GeneMGI:1919367Synonyms: Mak3p, 2600005K24Rik, +4 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Embryo Growth/size/body region Mortality/aging

17 No significant impact

2 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged epididymis1 supporting datasetNaa50em1(IMPC)MbpheterozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetNaa50em1(IMPC)MbpheterozygoteE15.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetNaa50em1(IMPC)MbphomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsNaa50em1(IMPC)MbphomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetNaa50em1(IMPC)MbphomozygoteE15.5N/A * 
edema1 supporting datasetNaa50em1(IMPC)MbpheterozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Naa50em1(IMPC)MbpExon Deletionmouse
Naa50tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Naa50tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Naa50tm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Naa50tm2e(KOMP)MbpTargeted, non-conditional alleleES Cell

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