Dusp11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Dusp11tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.41x10-5 | ||
| abnormal cornea morphology | 1 supporting dataset | Dusp11tm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.6x10-6 | ||
| abnormal locomotor behavior | 1 supporting dataset | Dusp11tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.83x10-6 | ||
| prolonged QRS complex duration | 1 supporting dataset | Dusp11tm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.96x10-5 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Dusp11tm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.83x10-5 |
| | | | | | | | | | |
External links
No external links available for Dusp11.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Dusp11tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Dusp11tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Dusp11tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Dusp11tm42136(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |