Phf7 | PHD finger protein 7

GeneMGI:1919088Synonyms: 1700006H01Rik, 1700010P14Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Reproductive system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetPhf7em1(IMPC)WtsihomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetPhf7tm1b(EUCOMM)HmguhomozygoteEarly adult3.83x10-5 
male infertility1 supporting datasetPhf7tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Phf7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Phf7em1(IMPC)WtsiDeletionmouse
Phf7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Phf7tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Phf7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Phf7tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Phf7tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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