Ulk3 | unc-51-like kinase 3
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Renal/urinary system
12 No significant impact
5 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Early adult | 4.12x10-9 | ||
| decreased circulating serum albumin level | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Early adult | 7.6x10-6 | ||
| enlarged lymph nodes | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged prostate gland | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| enlarged lymph nodes | 2 supporting datasets | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal epididymis morphology | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| small testis | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal seminal vesicle morphology | 1 supporting dataset | Ulk3em2(IMPC)Tcp | homozygote | Late adult | N/A * |
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Human diseases caused by Ulk3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ulk3.
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| Ulk3em2(IMPC)Tcp | Exon Deletion | | mouse |