Jmjd1c | jumonji domain containing 1C

GeneMGI:1918614Synonyms: TRIP8, D630035I23Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Skeleton Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

mydriasis1 supporting datasetJmjd1ctm1a(EUCOMM)WtsiheterozygoteEarly adult2.43x10-7 
preweaning lethality, incomplete penetrance1 supporting datasetJmjd1ctm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
vertebral transformation1 supporting datasetJmjd1ctm1a(EUCOMM)WtsiheterozygoteEarly adult2.53x10-8 
abnormal iris morphology1 supporting datasetJmjd1ctm1a(EUCOMM)WtsiheterozygoteEarly adult8.99x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Jmjd1ctm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Jmjd1ctm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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