Kbtbd12 | kelch repeat and BTB (POZ) domain containing 12
Physiological systems
21 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Digestive/alimentary Vision/eye
19 No significant impact
3 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| microphthalmia | 2 supporting datasets | Kbtbd12em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 2 supporting datasets | Kbtbd12em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal cecum morphology | 1 supporting dataset | Kbtbd12em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged cecum | 1 supporting dataset | Kbtbd12em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Kbtbd12 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Kbtbd12.
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| Kbtbd12em1(IMPC)Mbp | Inter-exon deletion | | mouse |
| Kbtbd12tm466023(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |