Nol8 | nucleolar protein 8

GeneMGI:1918180Synonyms: 5730412B09Rik, 4921532D18Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased fasting circulating glucose level	1 supporting dataset	Nol8^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.78x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Nol8^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased startle reflex	1 supporting dataset	Nol8^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.46x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nol8.

Associated images

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Histopathology

There is no histopathology data found for Nol8.

IMPC related publications

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External links

No external links available for Nol8.

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*Nol8^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Nol8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nol8^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nol8^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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