Usp46 | ubiquitin specific peptidase 46

GeneMGI:1916977Synonyms: 2410018I08Rik, 1190009E20Rik

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating triglyceride level	1 supporting dataset	Usp46^{em1(IMPC)Marc}	homozygote	Early adult	2.47x10^-5
increased basophil cell number	2 supporting datasets	Usp46^{em1(IMPC)Marc}	homozygote	Early adult	5.54x10^-25
increased eosinophil cell number	2 supporting datasets	Usp46^{em1(IMPC)Marc}	homozygote	Early adult	2.16x10^-12
increased circulating cholesterol level	1 supporting dataset	Usp46^{em1(IMPC)Marc}	homozygote	Early adult	2.52x10^-5
increased mean corpuscular volume	1 supporting dataset	Usp46^{em1(IMPC)Marc}	homozygote	Early adult	7.91x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp46.

Associated images

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Histopathology

There is no histopathology data found for Usp46.

IMPC related publications

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External links

No external links available for Usp46.

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*Usp46^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Usp46^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

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