Hilpda | hypoxia inducible lipid droplet associated
Physiological systems
7 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Muscle Cardiovascular system
5 No significant impact
17 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased heart left ventricle size | 1 supporting dataset | Hilpdaem1(IMPC)Mhzh | homozygote | Early adult | 5.46x10-5 | ||
| decreased cardiac muscle contractility | 2 supporting datasets | Hilpdaem1(IMPC)Mhzh | homozygote | Early adult | 1.26x10-5 | ||
| thin ventricular wall | 1 supporting dataset | Hilpdaem1(IMPC)Mhzh | homozygote | Early adult | 2x10-5 |
| | | | | | | | | | |
Human diseases caused by Hilpda mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Hilpda.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Hilpdaem1(IMPC)Mhzh | Deletion | | mouse |
| Hilpdatm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Hilpdatm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |