Fcmr | Fc fragment of IgM receptor

GeneMGI:1916419Synonyms: Faim3, 1810037B05Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Endocrine/exocrine gland Nervous system

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged adrenal glands1 supporting datasetFcmrtm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetFcmrtm1b(KOMP)WtsihomozygoteEarly adult9.72x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Fcmr mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Fcmrtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fcmrtm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Fcmrtm45241(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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