Trim15 | tripartite motif-containing 15
Physiological systems
21 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Behavior/neurological
20 No significant impact
3 Not tested
Data collections
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
36Embryo tissues
| abnormal vocalization | 1 supporting dataset | Trim15tm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.51x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| blood | heterozygote | n/a | n/a | 0% (0/17) |
| bone | heterozygote | n/a | 50% (1/2) | 0% (0/394) |
| bone marrow | heterozygote | n/a | n/a | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/2) | 7.75% (22/284) |
Human diseases caused by Trim15 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Trim15.
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| Trim15tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Trim15tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Trim15tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |