Mtmr14 | myotubularin related protein 14
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
18 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased startle reflex | 4 supporting datasets | Mtmr14tm1a(KOMP)Wtsi | homozygote | Early adult | 5.67x10-6 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Mtmr14tm1a(KOMP)Wtsi | homozygote | Early adult | 5.47x10-5 | ||
| increased lactate dehydrogenase level | 1 supporting dataset | Mtmr14tm1a(KOMP)Wtsi | homozygote | Early adult | 3.37x10-5 | ||
| increased circulating amylase level | 1 supporting dataset | Mtmr14tm1a(KOMP)Wtsi | homozygote | Early adult | 8.02x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Mtmr14tm1a(KOMP)Wtsi | homozygote | Early adult | 6.76x10-9 |
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Human diseases caused by Mtmr14 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Mtmr14.
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| Mtmr14tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Mtmr14tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |