Srpx2 | sushi-repeat-containing protein, X-linked 2

GeneMGI:1916042Synonyms: 1110039C07Rik

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

19 No significant impact

4 Not tested

Gene metrics:1Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating phosphate level1 supporting datasetSrpx2em1(IMPC)HmguhomozygoteEarly adult4.58x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Srpx2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Srpx2em1(IMPC)HmguExon Deletionmouse
Srpx2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Srpx2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Srpx2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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