Trp53inp2 | transformation related protein 53 inducible nuclear protein 2

GeneMGI:1915978Synonyms: Tp53inp2, 1110029F20Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Liver/biliary system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	2 supporting datasets	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	2.8x10^-7
abnormal testis morphology	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged testis	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	2 supporting datasets	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	3 supporting datasets	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	8.32x10^-5
enlarged lymph nodes	1 supporting dataset	Trp53inp2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trp53inp2.

Associated images

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Histopathology

There is no histopathology data found for Trp53inp2.

IMPC related publications

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External links

No external links available for Trp53inp2.

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*Trp53inp2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Trp53inp2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Trp53inp2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell

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