Steap3 | STEAP family member 3

GeneMGI:1915678Synonyms: pHyde, 1010001D01Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased hematocrit	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.13x10^-34
decreased hemoglobin content	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.1x10^-40
hyperactivity	4 supporting datasets	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.12x10^-6
hyperactivity	5 supporting datasets	Steap3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.85x10^-6
decreased mean corpuscular hemoglobin	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.71x10^-128
increased erythrocyte cell number	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.01x10^-130
thrombocytosis	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.39x10^-12
decreased mean corpuscular volume	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	0
decreased hematocrit	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.11x10^-8
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Steap3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.86x10^-22

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Steap3.

Associated images

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Histopathology

There is no histopathology data found for Steap3.

IMPC related publications

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External links

No external links available for Steap3.

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*Steap3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Steap3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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