Golt1a | golgi transport 1A
Physiological systems
15 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
13 No significant impact
9 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| thrombocytopenia | 1 supporting dataset | Golt1atm1b(KOMP)Wtsi | homozygote | Early adult | 8.15x10-5 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Golt1atm1b(KOMP)Wtsi | homozygote | Early adult | 2.48x10-12 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Golt1atm1b(KOMP)Wtsi | homozygote | Early adult | 8.88x10-16 | ||
| increased circulating bilirubin level | 1 supporting dataset | Golt1atm1b(KOMP)Wtsi | homozygote | Early adult | 6.7x10-5 | ||
| decreased circulating glucose level | 1 supporting dataset | Golt1atm1b(KOMP)Wtsi | homozygote | Early adult | 6.53x10-5 |
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Human diseases caused by Golt1a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Golt1a.
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| Golt1atm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Golt1atm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Golt1atm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |