Ino80 | INO80 complex subunit

GeneMGI:1915392Synonyms: Inoc1, 2310079N15Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Behavior/neurological Cardiovascular system Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

44Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased aggression	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	3.9x10^-6
abnormal vocalization	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	1.61x10^-5
decreased locomotor activity	5 supporting datasets	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	2.84x10^-9
preweaning lethality, incomplete penetrance	1 supporting dataset	Ino80^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	N/A ^*
prolonged QRS complex duration	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	4.42x10^-5
decreased exploration in new environment	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	2.48x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Ino80^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ino80.

Associated images

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Histopathology

There is no histopathology data found for Ino80.

IMPC related publications

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External links

No external links available for Ino80.

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*Ino80^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ino80^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ino80^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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