Fam32a | family with sequence similarity 32, member A
Physiological systems
22 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Endocrine/exocrine gland Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging Renal/urinary system
15 No significant impact
2 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Fam32aem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| enlarged kidney | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| anophthalmia | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Fam32aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal adrenal gland morphology | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Fam32aem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Fam32aem1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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Human diseases caused by Fam32a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Fam32a.
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| Fam32aem1(IMPC)Mbp | Exon Deletion | | mouse |
| Fam32atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Fam32atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Fam32atm238604(L1L2_Bact_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |