Mak16 | MAK16 homolog
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Mak16em1(IMPC)J | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Mak16em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| abnormal vocalization | 1 supporting dataset | Mak16em1(IMPC)J | heterozygote | Early adult | 4.94x10-5 |
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Human diseases caused by Mak16 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Mak16.
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| Mak16em1(IMPC)J | Exon Deletion | | mouse |
| Mak16tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Mak16tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Mak16tm83896(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |