Plpp3 | phospholipid phosphatase 3

GeneMGI:1915166Synonyms: D4Bwg0538e, PRG-2, +4 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetPlpp3tm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
increased circulating creatinine level1 supporting datasetPlpp3tm1b(EUCOMM)HmguheterozygoteEarly adult8.66x10-9 
preweaning lethality, complete penetrance1 supporting datasetPlpp3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetPlpp3tm1b(EUCOMM)HmguheterozygoteEarly adult5.32x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Plpp3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Plpp3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Plpp3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Plpp3tm39134(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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