Iah1 | isoamyl acetate-hydrolyzing esterase 1 homolog
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Cardiovascular system
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased prepulse inhibition | 1 supporting dataset | Iah1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.98x10-5 | ||
| prolonged QT interval | 1 supporting dataset | Iah1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.76x10-10 | ||
| prolonged ST segment | 1 supporting dataset | Iah1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.38x10-12 | ||
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Iah1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.94x10-6 |
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Human diseases caused by Iah1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Iah1.
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| Iah1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Iah1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Iah1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Iah1tm79462(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |