Hoga1 | 4-hydroxy-2-oxoglutarate aldolase 1

GeneMGI:1914682Synonyms: Npl2, Dhdpsl, +1 more

Physiological systems

3 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

2 No significant impact

21 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased thigmotaxis	2 supporting datasets	Hoga1^em1(IMPC)Bay	homozygote	Early adult	8.84x10^-5
abnormal behavior	1 supporting dataset	Hoga1^em1(IMPC)Bay	homozygote	Early adult	8.94x10^-5
decreased anxiety-related response	1 supporting dataset	Hoga1^em1(IMPC)Bay	homozygote	Early adult	5.18x10^-6
hyperactivity	2 supporting datasets	Hoga1^em1(IMPC)Bay	homozygote	Early adult	1.46x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hoga1.

Associated images

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Histopathology

There is no histopathology data found for Hoga1.

IMPC related publications

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External links

No external links available for Hoga1.

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*Hoga1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Hoga1^{tm119301(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Hoga1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Hoga1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hoga1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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