Cdc37l1 | cell division cycle 37-like 1
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton
13 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 6 supporting datasets | Cdc37l1em1(IMPC)J | homozygote | Early adult | 9.65x10-11 | ||
| abnormal auditory brainstem response | 1 supporting dataset | Cdc37l1em1(IMPC)J | homozygote | Early adult | 9.09x10-5 | ||
| decreased bone mineral density | 1 supporting dataset | Cdc37l1em1(IMPC)J | homozygote | Early adult | 9.57x10-5 | ||
| cataract | 1 supporting dataset | Cdc37l1em1(IMPC)J | homozygote | Early adult | 3.23x10-5 |
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Human diseases caused by Cdc37l1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cdc37l1.
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| Cdc37l1em1(IMPC)J | Exon Deletion | | mouse |
| Cdc37l1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |