Ptpmt1 | protein tyrosine phosphatase, mitochondrial 1
Physiological systems
19 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
18 No significant impact
5 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:41Adult tissues
29Embryo tissues
embryonic lethality prior to organogenesis | 1 supporting dataset | Ptpmt1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Ptpmt1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | n/a | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
eye | heterozygote | n/a | 0% (0/2) | 0% (0/335) |
heart | heterozygote | n/a | 0% (0/2) | 0.36% (2/550) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ptpmt1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.