Dnajc5b | DnaJ heat shock protein family (Hsp40) member C5 beta
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Cardiovascular system
17 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| shortened ST segment | 1 supporting dataset | Dnajc5btm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.15x10-9 | ||
| decreased exploration in new environment | 1 supporting dataset | Dnajc5btm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.5x10-13 | ||
| shortened QT interval | 1 supporting dataset | Dnajc5btm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.78x10-8 |
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Human diseases caused by Dnajc5b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Dnajc5b.
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| Dnajc5btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Dnajc5btm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Dnajc5btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Dnajc5btm45875(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |