Tmed6 | transmembrane p24 trafficking protein 6
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Endocrine/exocrine gland Growth/size/body region Liver/biliary system Behavior/neurological
16 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal pancreas morphology | 1 supporting dataset | Tmed6em1(IMPC)Rbrc | homozygote | Early adult | N/A * | ||
| enlarged liver | 1 supporting dataset | Tmed6em1(IMPC)Rbrc | homozygote | Late adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Tmed6em1(IMPC)Rbrc | homozygote | Late adult | N/A * | ||
| decreased exploration in new environment | 1 supporting dataset | Tmed6em1(IMPC)Rbrc | homozygote | Early adult | 5.59x10-5 | ||
| small pancreas | 1 supporting dataset | Tmed6em1(IMPC)Rbrc | homozygote | Early adult | N/A * |
| | | | | | | | | | |
Human diseases caused by Tmed6 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tmed6.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Tmed6em1(IMPC)Rbrc | Indel | | mouse |
| Tmed6tm374987(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |