Setd6 | SET domain containing 6

GeneMGI:1913333Synonyms: 0610039J04Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating aspartate transaminase level	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.32x10^-7
increased circulating potassium level	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	6.32x10^-5
hyperactivity	2 supporting datasets	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.6x10^-9
increased circulating alanine transaminase level	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.43x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Late adult	2.51x10^-5
female infertility	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Late adult	2.16x10^-7
sclerocornea	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.2x10^-12
increased erythrocyte cell number	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Late adult	1.41x10^-7
increased circulating bilirubin level	1 supporting dataset	Setd6^{tm1.1(KOMP)Mbp}	homozygote	Early adult	3.24x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setd6.

Associated images

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Histopathology

There is no histopathology data found for Setd6.

IMPC related publications

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External links

No external links available for Setd6.

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*Setd6^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Setd6^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Setd6^{tm463066(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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