Psmd14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14

GeneMGI:1913284Synonyms: 2610312C03Rik, Pad1, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Mortality/aging Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased basophil cell number2 supporting datasetsPsmd14tm1b(NCOM)CmhdheterozygoteEarly adult1.63x10-13 
increased heart weight1 supporting datasetPsmd14tm1b(NCOM)CmhdheterozygoteEarly adult1.54x10-5 
preweaning lethality, complete penetrance1 supporting datasetPsmd14tm1b(NCOM)CmhdhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Psmd14tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Psmd14tm1b(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)mouse

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