Gp6 | glycoprotein 6 platelet
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Limbs/digits/tail Hearing/vestibular/ear Vision/eye Hematopoietic system Skeleton
12 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased lymphocyte cell number | 1 supporting dataset | Gp6tm2b(EUCOMM)Hmgu | homozygote | Early adult | 6.71x10-6 | ||
| abnormal vibrissa morphology | 1 supporting dataset | Gp6tm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.16x10-5 | ||
| long tibia | 2 supporting datasets | Gp6tm2b(EUCOMM)Hmgu | homozygote | Early adult | 2.72x10-5 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Gp6tm2b(EUCOMM)Hmgu | homozygote | Early adult | 5.11x10-5 |
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Human diseases caused by Gp6 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Gp6.
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| Gp6tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gp6tm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gp6tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |