Tacstd2 | tumor-associated calcium signal transducer 2

GeneMGI:1861606Synonyms: GA733-1, Ly97, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Vision/eye

17 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetTacstd2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetTacstd2em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetTacstd2em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetTacstd2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Tacstd2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Tacstd2em1(IMPC)MbpWhole-gene deletionmouse

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