Krt71 | keratin 71
Physiological systems
10 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Pigmentation Integument
8 No significant impact
14 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal coat/hair pigmentation | 2 supporting datasets | Krt71em1(IMPC)Bay | homozygote | Early adult | 5.18x10-5 | ||
abnormal coat appearance | 3 supporting datasets | Krt71em1(IMPC)Bay | homozygote | Early adult | 1.89x10-12 | ||
abnormal coat/ hair morphology | 2 supporting datasets | Krt71em1(IMPC)Bay | homozygote | Early adult | 3.7x10-10 |
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Human diseases caused by Krt71 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Krt71.
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Krt71em1(IMPC)Bay | Exon Deletion | | mouse |
Krt71tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Krt71tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Krt71tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
Krt71tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |