Krt71 | keratin 71

GeneMGI:1861586Synonyms: Cu, Krt2-6g, +4 more

Physiological systems

10 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Pigmentation Integument

8 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation2 supporting datasetsKrt71em1(IMPC)BayhomozygoteEarly adult5.18x10-5 
abnormal coat appearance3 supporting datasetsKrt71em1(IMPC)BayhomozygoteEarly adult1.89x10-12 
abnormal coat/ hair morphology2 supporting datasetsKrt71em1(IMPC)BayhomozygoteEarly adult3.7x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by Krt71 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Krt71em1(IMPC)BayExon Deletionmouse
Krt71tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Krt71tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Krt71tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Krt71tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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