H1f5 | H1.5 linker histone, cluster member

GeneMGI:1861461Synonyms: H1f5, H1.5, +3 more

Physiological systems

9 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Skeleton

8 No significant impact

15 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetH1f5em1(IMPC)BayhomozygoteEarly adult2.93x10-5 
decreased bone mineral density1 supporting datasetH1f5em1(IMPC)BayhomozygoteEarly adult1.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by H1f5 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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H1f5em1(IMPC)BayWhole-gene deletionmouse

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