Panx1 | pannexin 1

GeneMGI:1860055

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal behavior	1 supporting dataset	Panx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.85x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Panx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.42x10^-7
decreased circulating serum albumin level	1 supporting dataset	Panx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.15x10^-7
decreased thigmotaxis	2 supporting datasets	Panx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.84x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Panx1.

Associated images

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Histopathology

There is no histopathology data found for Panx1.

IMPC related publications

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External links

No external links available for Panx1.

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*Panx1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Panx1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Panx1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Panx1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Panx1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Panx1^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes